Onent is because of increased myocardial fibrosis, ensuing in lowered end-diastolic volume [2]. The early ingredient is characterised by impaired active peace. Early relaxation occurs when Ca2+ is removed from the cytoplasm in to the SR by means of SERCA2a and away from the cell by the NCX, and reflects dissociation of Ca2+ from contractile myofilaments. SERCA2a is often a membrane protein that ca


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